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Literature summary for 2.5.1.21 extracted from

  • Koyama, T.; Ogura, K.; Seto, S.
    Substrate specificity of squalene synthetase (1980), Biochim. Biophys. Acta, 617, 218-224.
    View publication on PubMed

General Stability

General Stability Organism
detergent, e.g. deoxycholate, destabilizes Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Sus scrofa
-
-

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-3,7,10-trimethylundeca-2,6-dienyl diphosphate + NADPH weak Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7,11-trimethyldodeca-2,6-dienyl diphosphate + NADPH
-
Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7,12-trimethyltrideca-2,6-dienyl diphosphate + NADPH weak Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7-dimethyldodeca-2,6-dienyl diphosphate + NADPH
-
Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7-dimethyltetradeca-2,6-dienyl diphosphate + NADPH weak Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7-dimethyltrideca-2,6-dienyl diphosphate + NADPH weak Sus scrofa diphosphate + ?
-
?
(2E,6E)-3,7-dimethylundeca-2,6-dienyl diphosphate + NADPH weak Sus scrofa diphosphate + ?
-
?
additional information specificity overview Sus scrofa ?
-
?
additional information replacement of 3-methyl of farnesyl diphosphate by an ethyl group or introduction of a methyl group at C-4 results in a complete loss of activity Sus scrofa ?
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Sus scrofa