Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Saccharomyces cerevisiae | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | most effective in stimulation of squalene formation, half-maximal activity at 2.5 mM | Saccharomyces cerevisiae | |
Mg2+ | Mn2+ is more effective than Mg2+ in activation of dehydrosqualene formation | Saccharomyces cerevisiae | |
Mn2+ | more effective than Mg2+ in activation of dehydrosqualene formation | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate | in presence of Mn2+ | Saccharomyces cerevisiae | 12,13-cis-dehydrosqualene + diphosphate | 12-cis-dehydrosqualene + diphosphate | ? | |
farnesyl diphosphate + NAD(P)H | - |
Saccharomyces cerevisiae | squalene + diphosphate + NAD(P)+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Saccharomyces cerevisiae |