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Literature summary for 2.5.1.19 extracted from

  • Sutton, K.A.; Breen, J.; Russo, T.A.; Schultz, L.W.; Umland, T.C.
    Crystal structure of 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase from the ESKAPE pathogen Acinetobacter baumannii (2016), Acta Crystallogr. Sect. F, 72, 179-187.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.19

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta (DE3) cells Acinetobacter baumannii

Crystallization (Commentary)

Crystallization (Comment) Organism
microbatch under oil method, using 100 mM bis-Tris propane pH 7.0, 100 mM potassium bromide, 40% (w/v) PEG 8000 Acinetobacter baumannii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + 3-phosphoshikimate Acinetobacter baumannii
-
 phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
-
 ?
phosphoenolpyruvate + 3-phosphoshikimate Acinetobacter baumannii 307-0294
-
 phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
-
 ?

Organism

Organism UniProt Comment Textmining
Acinetobacter baumannii
-
-
-
Acinetobacter baumannii 307-0294
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HiTrap column chromatography and Superdex 200 gel filtration Acinetobacter baumannii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + 3-phosphoshikimate
-
 Acinetobacter baumannii phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
-
 ?
phosphoenolpyruvate + 3-phosphoshikimate
-
 Acinetobacter baumannii 307-0294 phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
-
 ?

Synonyms

Synonyms Comment Organism
5-enol-pyruvylshikimate-3-phosphate synthase
-
 Acinetobacter baumannii
AroA
-
 Acinetobacter baumannii
EPSP synthase
-
 Acinetobacter baumannii