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Literature summary for 2.5.1.18 extracted from

  • Rose, C.; Praulins, G.; Armstrong, S.D.; Casas-Sanchez, A.; Davis, J.; Molyneux, G.; Yunta, C.; Stead, Z.; Prescott, M.; Perally, S.; Rutter, A.; Makepeace, B.L.; La Course, E.J.; Acosta-Serrano, A.
    Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite (2019), Parasitology, 146, 1773-1784 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.18

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Onchocerca ochengi 5829
-

Organism

Organism UniProt Comment Textmining
Onchocerca ochengi
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein the enzyme exists of at least four glycoforms. There are 6 potential N-glycosylation sites at Asn5, Asn7, Asn60, Asn79, Asn134 and Asn144 Onchocerca ochengi

Purification (Commentary)

Purification (Comment) Organism
S-hexylglutathione-affinity column chromatography and concanavalin A-agarose column chromatography Onchocerca ochengi

Source Tissue

Source Tissue Comment Organism Textmining
adult
-
 Onchocerca ochengi
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + 1-chloro-2,4-dinitrobenzene
-
 Onchocerca ochengi chloride + 2,4-dinitrophenyl-glutathione
-
 ?
additional information the purified enzyme shows prostaglandin synthase activity Onchocerca ochengi ?
-
-

Subunits

Subunits Comment Organism
? x * 35000, SDS-PAGE Onchocerca ochengi

Synonyms

Synonyms Comment Organism
GST1b
-
 Onchocerca ochengi
Sigma class GST
-
 Onchocerca ochengi