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Literature summary for 2.5.1.18 extracted from

  • Fujikawa, Y.; Urano, Y.; Komatsu, T.; Hanaoka, K.; Kojima, H.; Terai, T.; Inoue, H.; Nagano, T.
    Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells (2008), J. Am. Chem. Soc., 130, 14533-14543.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.232
-
3,4-dinitrobenzanilide in phosphate buffered saline, pH 7.4, at 37°C Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P09211
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-
HL-60 cell
-
Homo sapiens
-
HT-1080 cell
-
Homo sapiens
-
HuCCT-1 cell
-
Homo sapiens
-
HUVEC cell
-
Homo sapiens
-
OUS-11 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-[[(3,4-dinitrophenyl)carbonyl]amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid + glutathione
-
Homo sapiens ?
-
?
5-[[(3,4-dinitrophenyl)carbonyl]amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid + glutathione
-
Homo sapiens ?
-
?
glutathione + 1-chloro-2,4-dinitrobenzene
-
Homo sapiens S-(2,4-dinitrophenyl)glutathione + HCl
-
?
glutathione + 2-methyl-4-nitrobenzyl alcohol
-
Homo sapiens ?
-
?
glutathione + 3,4-dinitrobenzanilide
-
Homo sapiens ?
-
?
glutathione + 4-chloro-3-nitroacetophenone
-
Homo sapiens ?
-
?
glutathione + 4-chloro-3-nitrobenzophenone
-
Homo sapiens ?
-
?
glutathione + 4-fluoro-3-nitrobenzanilide
-
Homo sapiens ?
-
?
additional information pentafluorobenzanilide and 4-chloro-3-nitrobenzanilide are no substrates Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
glutathione S-transferase
-
Homo sapiens
GSTP1
-
Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
367
-
3,4-dinitrobenzanilide in phosphate buffered saline, pH 7.4, at 37°C Homo sapiens