Literature summary for 2.5.1.18 extracted from

Huang, C.H.; Liew, L.M.; Mah, K.W.; Kuo, I.C.; Lee, B.W.; Chua, K.Y.
Characterization of glutathione S-transferase from dust mite, Der p 8 and its immunoglobulin E cross-reactivity with cockroach glutathione S-transferase (2006), Clin. Exp. Allergy, 36, 369-376.

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Cloned(Commentary)

Cloned (Comment)	Organism
Der p 8, DNA and amino acid sequence determination and analysis, expression of Der p 8 in Pichia pastoris srain GS115	Dermatophagoides pteronyssinus

Protein Variants

Protein Variants	Comment	Organism
E46Q/E106K/I149V/N!60Y/H167R/R184K	naturally occuring polymorphisms, nucleotide difference between isozymes Der p 8 and Der p 2, overview	Dermatophagoides pteronyssinus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
25705	-	x * 25705, isozyme Der p 8, sequence calcualtion	Dermatophagoides pteronyssinus

Organism

Organism	UniProt	Comment	Textmining
Dermatophagoides pteronyssinus	-	dust mite, isozymes Der p 8 and Der p 2	-
Periplaneta americana	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
native enzyme by glutathione affinity chromatography	Periplaneta americana
recombinant Der p 8 from Pichia pastoris by glutathione affinity chromatography, native enzyme Der p 2 by glutathione affinity chromatography	Dermatophagoides pteronyssinus

Subunits

Subunits	Comment	Organism
?	x * 25705, isozyme Der p 8, sequence calcualtion	Dermatophagoides pteronyssinus

Synonyms

Synonyms	Comment	Organism
allergen Der p 2	-	Dermatophagoides pteronyssinus
allergen Der p 8	-	Dermatophagoides pteronyssinus
glutathione S-transferase	-	Periplaneta americana
glutathione S-transferase	-	Dermatophagoides pteronyssinus
GST	-	Periplaneta americana
GST	-	Dermatophagoides pteronyssinus

pI Value

Organism	Comment	pI Value Maximum	pI Value
Dermatophagoides pteronyssinus	isozyme Der p 2	-	6.3
Dermatophagoides pteronyssinus	isozyme Der p 8	-	8.5

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Release 2023.1 (January 2023)