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Literature summary for 2.5.1.18 extracted from
- Isolation and characterization of an anionic glutathione S-transferase from rat liver cytosol (1983), Biochem. Biophys. Res. Commun., 111, 840-846.
General Stability
| General Stability | Organism |
|---|---|
| loss of activity during purification due to irreversible inactivation | Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.23 | - |
glutathione | - |
Rattus norvegicus |  |
| 0.94 | - |
1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 26000 | - |
2 * 26000, SDS-PAGE | Rattus norvegicus |
| 49000 | 54000 | gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| homogeneity, anionic enzyme | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 10.83 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + 1,2-dichloro-4-nitrobenzene | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + 1,2-epoxy-3-(4-nitrophenoxy)propane | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | S-2,4-dinitrophenylglutathione + HCl | - |
? | |
| glutathione + 4-nitrobenzyl chloride | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + 4-nitrophenyl acetate | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + cumene hydroperoxide | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + ethacrynic acid | - |
Rattus norvegicus | ? | - |
? | |
| additional information | specificity | Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 26000, SDS-PAGE | Rattus norvegicus |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 7.33 | - |
glutathione | - |
Rattus norvegicus | |
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