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Literature summary for 2.5.1.18 extracted from

  • Ketterer, B.; Beale, D.; Meyer, D.
    The structure and multiple functions of glutathione transferases (1982), Biochem. Soc. Trans., 10, 82-84.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RX + glutathione Rattus norvegicus detoxification of electrophilic products of cytochrome P-450-dependent reactions, toxic catabolite of heme, bilirubin is bound and thereby neutralized HX + R-S-glutathione
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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at least 7 forms
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + 1-chloro-2,4-dinitrobenzene
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Rattus norvegicus S-2,4-dinitrophenylglutathione + HCl
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?
RX + glutathione detoxification of electrophilic products of cytochrome P-450-dependent reactions, toxic catabolite of heme, bilirubin is bound and thereby neutralized Rattus norvegicus HX + R-S-glutathione
-
?

Subunits

Subunits Comment Organism
dimer dimer composed of two of the following subunits: Ya MW 23000, Yb MW 23500, Yc MW 25000, SDS-PAGE Rattus norvegicus