Any feedback?
Literature summary for 2.5.1.18 extracted from
- Microsomal glutathione S-transferase. Purification, initial characterization and demonstration that it is not identical to the cytosolic glutathione S-transferases A, B and C (1982), Eur. J. Biochem., 128, 243-248.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
| additional information | microsomal enzyme is clearly distinct from cytosolic | Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 14000 | - |
SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RX + glutathione | Rattus norvegicus | participates in detoxification | HX + R-S-glutathione | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| 36fold | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 30.9 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + 1,2-dichloro-4-nitrobenzene | - |
Rattus norvegicus | ? | - |
? | |
| glutathione + 1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | S-2,4-dinitrophenylglutathione + HCl | - |
? | |
| additional information | no substrate: bromosulfophthalein | Rattus norvegicus | ? | - |
? | |
| additional information | no substrate: 4-nitrobenzyl chloride | Rattus norvegicus | ? | - |
? | |
| additional information | no substrate: 1,2-epoxy-3-(4-nitrophenoxy)propane | Rattus norvegicus | ? | - |
? | |
| additional information | no substrate: trans-4-phenyl-3-buten-2-one | Rattus norvegicus | ? | - |
? | |
| additional information | no substrate: ethacrynic acid | Rattus norvegicus | ? | - |
? | |
| RX + glutathione | RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange | Rattus norvegicus | HX + R-S-glutathione | - |
? | |
| RX + glutathione | participates in detoxification | Rattus norvegicus | HX + R-S-glutathione | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | more than one subunit | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
