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Literature summary for 2.5.1.16 extracted from

  • Das, M.; Singh, S.; Dubey, V.K.
    Novel inhibitors of ornithine decarboxylase of Leishmania parasite (LdODC): the parasite resists LdODC inhibition by overexpression of spermidine synthase (2016), Chem. Biol. Drug Des., 87, 352-360.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Leishmania donovani A4HS53
-
-

Source Tissue

Source Tissue Comment Organism Textmining
promastigote
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Leishmania donovani
-

Expression

Organism Comment Expression
Leishmania donovani the expression level of spermidine synthase level increases by 2fold after ornithine decarboxylaseinhibitor M-5 compound treatment and 1.5fold by ornithine decarboxylase inhibitor M-2 compound treatment up

General Information

General Information Comment Organism
physiological function the parasite resists ornithine decarboxylase inhibitors by overexpression of spermidine synthase mRNA Leishmania donovani