Literature summary for 2.5.1.15 extracted from

Maghsoodloorad, S.; Hosseinzadeh, N.; Haghighi, A.; Solgi, R.; Yusuf, M.; Hatam, G.
Amino acid mutation in Plasmodium vivax dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) genes in Hormozgan Province, southern Iran (2019), J. Vector Borne Dis., 56, 170-173 .

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Application

Application	Comment	Organism
medicine	the enzyme is important in predicting the emergence of drug resistance to sulphadoxine-pyrimethamine	Plasmodium vivax

Protein Variants

Protein Variants	Comment	Organism
A383G	high prevalence amino acid mutation observed in Hormozgan Province, southern Iran. The high prevalence of point mutation of Pvdhps genotype necessitates change in programmes and guidelines to eliminate Plasmodium vivax in future	Plasmodium vivax
D459A	high prevalence amino acid mutation observed in Hormozgan Province, southern Iran. The high prevalence of point mutation of Pvdhps genotype necessitates change in programmes and guidelines to eliminate Plasmodium vivax in future	Plasmodium vivax

Organism

Organism	UniProt	Comment	Textmining
Plasmodium vivax	Q6Y3G8	-	-

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Release 2023.1 (January 2023)