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Literature summary for 2.5.1.15 extracted from
- Effects of osmolytes on ligand binding to dihydropteroate synthase from Bacillus anthracis (2020), J. Phys. Chem. B, 124, 6212-6224 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli BL21 | Bacillus anthracis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the association rates of pterin diphosphate are mostly unaffected by the osmolytes, except for a 2fold decrease in the presence of 1 M trehalose | Bacillus anthracis |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate | Bacillus anthracis | - |
diphosphate + 7,8-dihydropteroate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus anthracis | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bacillus anthracis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate | - |
Bacillus anthracis | diphosphate + 7,8-dihydropteroate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DHPS | - |
Bacillus anthracis |
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Release 2023.1 (January 2023)
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