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Literature summary for 2.5.1.15 extracted from

  • Arif, S.; Khan, M.; Gardezi, S.; Abbas, Z.; Ali, G.
    A novel hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase (HPPK-DHPS) gene from a nutraceutical plant seabuckthorn, involved in folate pathway is predominantly expressed in fruit tissue (2016), Int. J. Agric. Biol., 18, 412-418.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
7,8-dihydropteroate
-
Hippophae rhamnoides
dihydrofolate
-
Hippophae rhamnoides
tetrahydrofolate-Glu
-
Hippophae rhamnoides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate Hippophae rhamnoides
-
diphosphate + 7,8-dihydropteroate
-
?

Organism

Organism UniProt Comment Textmining
Hippophae rhamnoides
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit
-
Hippophae rhamnoides
-
leaf
-
Hippophae rhamnoides
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate
-
Hippophae rhamnoides diphosphate + 7,8-dihydropteroate
-
?

Synonyms

Synonyms Comment Organism
HPPK-DHPS bifunctional enzyme with hydroxymethyldihydropterin pyrophosphokinase and dihydropteroate synthase activities Hippophae rhamnoides