Crystallization (Comment) | Organism |
---|---|
more putative structural model of five mutations in DHPS to explain sulfadoxine resistance, structural model based on crystal structures of Saccharomyces cerevisiae (PPPK-DHPS), Mycobacterium tuberculosis (DHPS), Bacillus anthracis (DHPS), and Escherichia coli (PPPK) | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
sulfadoxine | - |
Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate | Plasmodium falciparum | - |
diphosphate + 7,8-dihydropteroate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | Q27735 | fragment of dihydropteroate synthase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate | - |
Plasmodium falciparum | diphosphate + 7,8-dihydropteroate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
7,8-dihydropteroate synthase | - |
Plasmodium falciparum |
DHPS | - |
Plasmodium falciparum |
dihydropteroate synthetase | - |
Plasmodium falciparum |