BRENDA - Enzyme Database
show all sequences of 2.5.1.147

Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F(420) and FO biosynthesis

Choi, K.P.; Kendrick, N.; Daniels, L.; J. Bacteriol. 184, 2420-2428 (2002)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
His-tagged FbiC overexpressed in Escherichia coli
Mycobacterium tuberculosis variant bovis
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mycobacterium tuberculosis variant bovis
Q7U0G9
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Cloned(Commentary) (protein specific)
Commentary
Organism
His-tagged FbiC overexpressed in Escherichia coli
Mycobacterium tuberculosis variant bovis
General Information
General Information
Commentary
Organism
malfunction
four independent mutants that can not make F420 or the biosynthesis intermediate FO contain transposons inserted in the Mycobacterium bovis gene fbiC
Mycobacterium tuberculosis variant bovis
metabolism
the enzyme is essential for F420 production
Mycobacterium tuberculosis variant bovis
General Information (protein specific)
General Information
Commentary
Organism
malfunction
four independent mutants that can not make F420 or the biosynthesis intermediate FO contain transposons inserted in the Mycobacterium bovis gene fbiC
Mycobacterium tuberculosis variant bovis
metabolism
the enzyme is essential for F420 production
Mycobacterium tuberculosis variant bovis
Other publictions for EC 2.5.1.147
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
748030
Philmus
Biosynthetic versatility and ...
Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661
J. Am. Chem. Soc.
137
5406-5413
2015
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4
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1
1
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748607
Guerra-Lopez
-
Mycobacterium smegmatis mc2 1 ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis mc2 155
Microbiology
153
2724-2732
2007
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2
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2
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1
1
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746934
Graham
Identification of the 7,8-did ...
Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661, Mycolicibacterium smegmatis
Arch. Microbiol.
180
455-464
2003
1
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1
2
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8
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1
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3
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1
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2
2
2
2
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748075
Choi
Demonstration that fbiC is re ...
Mycobacterium tuberculosis variant bovis
J. Bacteriol.
184
2420-2428
2002
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