Any feedback?
Literature summary for 2.5.1.117 extracted from
- In vivo and in vitro evidence for the inhibition of homogentisate solanesyltransferase by cyclopyrimorate (2019), Pest Manag. Sci., 76, 3389-3394 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cyclopyrimorate | competitive inhibitor with respect to homogentisate and mixed non-competitive inhibitor with respect to farnesyl diphosphate | Arabidopsis thaliana |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0306 | - |
farnesyl diphosphate | at pH 8.0 and 32°C | Arabidopsis thaliana | |
| 0.1342 | - |
homogentisate | at pH 8.0 and 32°C | Arabidopsis thaliana | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 20 mM used in assay conditions | Arabidopsis thaliana | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| solanesyl diphosphate + homogentisate | Arabidopsis thaliana | - |
diphosphate + 2-methyl-6-solanesyl-1,4-benzoquinol + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q1ACB3 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| farnesyl diphosphate + homogentisate | - |
Arabidopsis thaliana | diphosphate + (3-(2E,6E)-farnesyl-2,5-dihydroxyphenyl)acetate | - |
? | |
| solanesyl diphosphate + homogentisate | - |
Arabidopsis thaliana | diphosphate + 2-methyl-6-solanesyl-1,4-benzoquinol + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HST | - |
Arabidopsis thaliana |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0056 | - |
cyclopyrimorate | with respect to homogentisate, at pH 8.0 and 32°C | Arabidopsis thaliana | |
| 0.0064 | - |
cyclopyrimorate | with respect to farnesyl diphosphate, at pH 8.0 and 32°C | Arabidopsis thaliana | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
