Any feedback?
Literature summary for 2.5.1.106 extracted from
- Rearrangements in the mechanisms of the indole alkaloid prenyltransferases (2013), Pure Appl. Chem., 85, 1935-1948.
No PubMed abstract available
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dimethylallyl diphosphate + brevianamide F | Aspergillus fumigatus | i.e. cyclo-L-Trp-L-Pro | diphosphate + tryprostatin B | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus fumigatus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dimethylallyl diphosphate + brevianamide F | i.e. cyclo-L-Trp-L-Pro | Aspergillus fumigatus | diphosphate + tryprostatin B | - |
? | |
| additional information | comparison of mechanisms of the indole alkaloid prenyltransferases. Tryprostatin B synthase catalyzes the normal C-2 prenylation of the indole ring in brevianamide F (cyclo-L-Trp-L-Pro). Mechanism includes an initial C-3 prenylation (either normal or reverse) followed by carbo cation rearrangements to give product | Aspergillus fumigatus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FtmPT1 | - |
Aspergillus fumigatus |
| tryprostatin B synthase | - |
Aspergillus fumigatus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
