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Literature summary for 2.5.1.10 extracted from

  • Mukherjee, S.; Basu, S.; Zhang, K.
    Farnesyl pyrophosphate synthase is essential for the promastigote and amastigote stages in Leishmania major (2019), Mol. Biochem. Parasitol., 230, 8-15 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Leishmania major Q4QBL1
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Leishmania major MHOM Q4QBL1
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-

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
farnesyl pyrophosphate synthase
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Leishmania major
FPPS
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Leishmania major

General Information

General Information Comment Organism
drug target the enzyme is a drug target for the treatment of cutaneous leishmaniasis Leishmania major
metabolism the enzyme catalyzes the formation of farnesyl pyrophosphate, a key intermediate for the biosynthesis of all isoprenoids Leishmania major
physiological function farnesyl pyrophosphate synthase is essential for the promastigote and amastigote stages in Leishmania major Leishmania major