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Literature summary for 2.4.2.9 extracted from

  • Hasegawa, N.; Abei, M.; Yokoyama, K.K.; Fukuda, K.; Seo, E.; Kawashima, R.; Nakano, Y.; Yamada, T.; Nakade, K.; Hamada, H.; Obata, Y.; Hyodo, I.
    Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters (2013), Int. J. Cancer, 133, 1479-1488.
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme increases the sensitivity to 5-fluorouracil in HaP-T1 cells in vitro Syrian hamster adenovirus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HaP-T1 cells Syrian hamster adenovirus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20000
-
x * 20000, SDS-PAGE Syrian hamster adenovirus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
uracil + 5-phospho-alpha-D-ribose 1-diphosphate Syrian hamster adenovirus
-
UMP + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Syrian hamster adenovirus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate
-
Syrian hamster adenovirus 5-fluoro-UMP + diphosphate
-
?
uracil + 5-phospho-alpha-D-ribose 1-diphosphate
-
Syrian hamster adenovirus UMP + diphosphate
-
?

Subunits

Subunits Comment Organism
? x * 20000, SDS-PAGE Syrian hamster adenovirus

Synonyms

Synonyms Comment Organism
UPRT
-
Syrian hamster adenovirus