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Literature summary for 2.4.2.9 extracted from
- Specific targeting of prostate cancer cells in vitro by the suicide gene/prodrug system, uracil phosphoribosyltransferase/5-fluorouracil, under the control of prostate-specific membrane antigen promoter/enhancer (2008), Prostate Cancer Prostatic. Dis., 12, 166-171.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the efficiacy of 5-fluorouracil-based chemotherapy in prostate cancers can be significantly improved by targeted expression of the suicide gene UPRT under the control of the human prostate-specific membrane antigen promotor/enhancer | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in LNCaP cells | Escherichia coli |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| uracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Escherichia coli | UMP + diphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UPRT | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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