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Literature summary for 2.4.2.9 extracted from
- Apoptotic induction with bifunctional E.coli cytosine deaminase-uracil phosphoribosyltransferase mediated suicide gene therapy is synergized by curcumin treatment in vitro (2008), Mol. Biotechnol., 39, 39-48.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | combination of 5-flurocytosine/cytosine deaminase-uracil phosphoribosyltransferase with curcumin can be a potential chemosensitization strategy for cancer treatment | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in BHK-21 cells and HAT-29 cells | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| uracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Escherichia coli | UMP + diphosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CD-UPRT | - |
Escherichia coli |
| cytosine deaminase-uracil phosphoribosyltransferase | bifunctional enzyme | Escherichia coli |
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Release 2023.1 (January 2023)
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