Activating Compound | Comment | Organism | Structure |
---|---|---|---|
alendronate | 1 mM, increases the initial rate of synthesis of 5-fluoro-UMP 2.5fold, increases the initial rate of synthesis of UMP 2.3fold | Saccharomyces cerevisiae | |
clodronate | 1 mM, increases the initial rate of synthesis of 5-fluoro-UMP 2fold, increases the initial rate of synthesis of UMP 1.9fold | Saccharomyces cerevisiae | |
etidronate | 1 mM, increases the initial rate of synthesis of 5-fluoro-UMP 2.8fold, increases the initial rate of synthesis of UMP 2.1fold | Saccharomyces cerevisiae | |
additional information | no activating effect with methylene biphosphonate | Saccharomyces cerevisiae | |
pamidronate | 1 mM, increases the initial rate of synthesis of 5-fluoro-UMP 2.6fold, increases the initial rate of synthesis of UMP 2.1fold | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Saccharomyces cerevisiae | 5-fluoro-UMP + diphosphate | - |
? | |
uracil + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Saccharomyces cerevisiae | UMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UPRT | - |
Saccharomyces cerevisiae |