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Literature summary for 2.4.2.8 extracted from

  • Stuer-Lauridsen, B.; Nygaard, P.
    Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs (1998), J. Bacteriol., 180, 457-463.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Halobacterium salinarum
-
-
-
Haloferax volcanii
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
870
-
substrate GMP, crude cell extract, pH 7.5, temperature not specified in the publication Halobacterium salinarum
2130
-
substrate IMP, crude cell extract, pH 7.5, temperature not specified in the publication Haloferax volcanii
2340
-
substrate IMP, crude cell extract, pH 7.5, temperature not specified in the publication Halobacterium salinarum
2450
-
substrate GMP, crude cell extract, pH 7.5, temperature not specified in the publication Haloferax volcanii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GMP + diphosphate
-
Halobacterium salinarum guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
?
GMP + diphosphate
-
Haloferax volcanii guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
?
IMP + diphosphate
-
Halobacterium salinarum hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
?
IMP + diphosphate
-
Haloferax volcanii hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
?

General Information

General Information Comment Organism
metabolism comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels Halobacterium salinarum
metabolism comparison of growth characteristics including intracellular protein levels, RNA content, and nucleotide pool sizes between the extreme halophile Halobacterium halobium and the moderate halophile Haloferax volcanii. The differences in the metabolism of purine bases and nucleosides and the sensitivity to purine analogs between the two halobacteria are reflected in differences in purine enzyme levels Haloferax volcanii