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Literature summary for 2.4.2.63 extracted from

  • Takeuchi, H.; Fernandez-Valdivia, R.; Caswell, D.; Nita-Lazar, A.; Rana, N.; Garner, T.; Weldeghiorghis, T.; Macnaughtan, M.; Jafar-Nejad, H.; Haltiwanger, R.
    Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase (2011), Proc. Natl. Acad. Sci. USA, 108, 16600-16605 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Drosophila melanogaster mutant clones Mus musculus
expressed in Drosophila melanogaster mutant clones Homo sapiens

Protein Variants

Protein Variants Comment Organism
G169E inactive Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ 10 mM used in assay conditions Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
additional information Homo sapiens the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine Mus musculus
-
UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
?
UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine Homo sapiens
-
UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Mus musculus ?
-
-
additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Homo sapiens ?
-
-
UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine
-
Mus musculus UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
?
UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine
-
Homo sapiens UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
?

Synonyms

Synonyms Comment Organism
Poglut
-
Mus musculus
Poglut
-
Homo sapiens
Rumi
-
Mus musculus
Rumi
-
Homo sapiens