BRENDA - Enzyme Database
show all sequences of 2.4.2.42

Presence of UDP-D-xylose: beta-D-glucoside alpha-1,3-D-xylosyltransferase involved in the biosynthesis of the Xylalpha1-3Glcbeta-Ser structure of glycoproteins in the human hepatoma cell line HepG2

Omichi, K.; Aoki, K.; Minamida, S.; Hase S.; Eur. J. Biochem. 245, 143-146 (1997)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Homo sapiens
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Homo sapiens
the enzyme is appears to be involved in the biosynthesis of the Xylalpha(1-3)Glcbeta-Ser structure of glycoproteins such as human blood coagulation factors VII and IX
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
Hep-G2 cell
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is appears to be involved in the biosynthesis of the Xylalpha(1-3)Glcbeta-Ser structure of glycoproteins such as human blood coagulation factors VII and IX
697698
Homo sapiens
?
-
-
-
-
UDP-D-xylose + 2-(pyridin-2-ylamino)ethyl beta-D-glucopyranoside
-
697698
Homo sapiens
UDP + 2-(pyridin-2-ylamino)ethyl 3-O-alpha-D-xylopyranosyl-beta-D-glucopyranoside
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
-
Homo sapiens
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6.6
7.6
pH 6.6: about 80% of maximal activity, pH 7.6: about 90% of maximal activity
Homo sapiens
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
-
Homo sapiens
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Homo sapiens
the enzyme is appears to be involved in the biosynthesis of the Xylalpha(1-3)Glcbeta-Ser structure of glycoproteins such as human blood coagulation factors VII and IX
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
Hep-G2 cell
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is appears to be involved in the biosynthesis of the Xylalpha(1-3)Glcbeta-Ser structure of glycoproteins such as human blood coagulation factors VII and IX
697698
Homo sapiens
?
-
-
-
-
UDP-D-xylose + 2-(pyridin-2-ylamino)ethyl beta-D-glucopyranoside
-
697698
Homo sapiens
UDP + 2-(pyridin-2-ylamino)ethyl 3-O-alpha-D-xylopyranosyl-beta-D-glucopyranoside
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
-
Homo sapiens
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6.6
7.6
pH 6.6: about 80% of maximal activity, pH 7.6: about 90% of maximal activity
Homo sapiens
Other publictions for EC 2.4.2.42
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
698648
Ishimizu
Purification and substrate spe ...
Bos taurus
J. Biochem.
141
593-600
2007
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-
-
-
-
-
5
2
1
2
-
1
-
2
-
-
1
-
-
1
1
-
5
-
1
-
-
-
1
1
-
-
-
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-
-
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-
-
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5
-
2
1
2
-
1
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-
1
-
1
1
-
5
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
697698
Omichi
Presence of UDP-D-xylose: beta ...
Homo sapiens
Eur. J. Biochem.
245
143-146
1997
-
-
-
-
-
-
-
-
1
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1
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1
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1
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2
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1
1
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-
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-
1
-
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1
-
-
-
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-
1
-
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2
-
-
-
-
-
1
1
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