Literature summary for 2.4.2.4 extracted from

Loo, W.T.; Chow, L.W.; Suzuki, T.; Ono, K.; Ishida, T.; Hirakawa, H.; Ohuchi, N.; Sasano, H.
Expression of thymidine phosphorylase and dihydropyrimidine dehydrogenase in human breast carcinoma cells and tissues (2009), Anticancer Res., 29, 2525-2530.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	capecitabine does not affect enzyme activity and expression	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	capecitabine does not affect enzyme activity and expression	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast carcinoma cell	-	Homo sapiens	-
BT-483 cell	-	Homo sapiens	-
MDA-MB-231 cell	-	Homo sapiens	-
additional information	enzyme expression analysis in cancer patients, overview	Homo sapiens	-

Expression

Organism	Comment	Expression
Homo sapiens	capecitabine does not affect enzyme activity and expression	additional information

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Release 2023.1 (January 2023)