Literature summary for 2.4.2.4 extracted from

Layman, R.M.; Thomas, D.G.; Griffith, K.A.; Smerage, J.B.; Helvie, M.A.; Roubidoux, M.A.; Diehl, K.M.; Newman, L.A.; Sabel, M.S.; Hayman, J.A.; Pierce, L.J.; Hayes, D.F.; Schott, A.F.
Neoadjuvant docetaxel and capecitabine and the use of thymidine phosphorylase as a predictive biomarker in breast cancer (2007), Clin. Cancer Res., 13, 4092-4097.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	thymidine phosphorylase expression is not up-regulated after docetaxel treatment	Homo sapiens

Application

Application	Comment	Organism
medicine	thymidine phosphorylase is a predictive biomarker in breast cancer	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
thymidine + phosphate	-	Homo sapiens	thymine + 2-deoxy-D-ribose 1-phosphate	-	?

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Release 2023.1 (January 2023)