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Literature summary for 2.4.2.30 extracted from

  • Menzel, S.; Rissiek, B.; Bannas, P.; Jakoby, T.; Miksiewicz, M.; Schwarz, N.; Nissen, M.; Haag, F.; Tholey, A.; Koch-Nolte, F.
    Nucleotide-induced membrane-proximal proteolysis controls the substrate specificity of T cell ecto-ADP-ribosyltransferase ARTC2.2 (2015), J. Immunol., 195, 2057-2066.
    View publication on PubMed
Search for more literature for 2.4.2.30

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK cells Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 30000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme itself is a target for P2X7-triggered ectodomain shedding at F239/S240 ?
-
 ?
NAD+ + (ADP-D-ribosyl)n-P2X7 ion channel Mus musculus
-
 nicotinamide + (ADP-D-ribosyl)n+1-P2X7 ion channel + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
anti-FLAG mAb column chromatography and gel filtration Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
T-cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme itself is a target for P2X7-triggered ectodomain shedding at F239/S240 Mus musculus ?
-
 ?
NAD+ + (ADP-D-ribosyl)n-P2X7 ion channel
-
 Mus musculus nicotinamide + (ADP-D-ribosyl)n+1-P2X7 ion channel + H+
-
 ?

Subunits

Subunits Comment Organism
? x * 30000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
ARTC2.2
-
 Mus musculus
ecto-ADP-ribosyltransferase
-
 Mus musculus