Literature summary for 2.4.2.30 extracted from

Werner, E.; Sohst, S.; Gropp, F.; Simon, D.; Wagner, H.; Kroeger, H.
Presence of poly (ADP-ribose) polymerase and poly (ADP-ribose) glycohydrolase in the dinoflagellate Crypthecodinium cohnii (1984), Eur. J. Biochem., 139, 81-86.

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Activating Compound

Activating Compound	Comment	Organism	Structure
DNA	required	Cryptothecodinium cohnii

Inhibitors

Inhibitors	Comment	Organism	Structure
5-Methylnicotinamide	0.15 mM, 31% inhibition	Cryptothecodinium cohnii
Benzamide	0.15 mM, 48% inhibition	Cryptothecodinium cohnii
nicotinamide	0.15 mM, 25% inhibition	Cryptothecodinium cohnii
theophylline	0.15 mM, 62% inhibition	Cryptothecodinium cohnii
thymidine	0.15 mM, 39% inhibition	Cryptothecodinium cohnii

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Cryptothecodinium cohnii	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Cryptothecodinium cohnii

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NAD+ + (ADP-D-ribosyl)n-acceptor	poly(ADP-ribosyl)ation of histone	Cryptothecodinium cohnii	nicotinamide + (ADP-D-ribosyl)n+1-acceptor	-	?

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Release 2023.1 (January 2023)