Cloned (Comment) | Organism |
---|---|
from cells of patients with T-cell acute lymphoblastic leukemia, DNA sequence analysis, 9p21 chromosome, topologic map | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme plays a role in purine and polyamine metabolism and in the regulation of transmethylation reactions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13126 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mononuclear cell | - |
Homo sapiens | - |
additional information | enzyme deficiency in malignant cells, partial or total deletions in the gene of leukemia cell lines of patients with T-cell acute lymphoblastic leukemia | Homo sapiens | - |
peripheral blood | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-deoxy-5'-methylthioadenosine + phosphate | - |
Homo sapiens | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? | |
5'-methylthioadenosine + phosphate | - |
Homo sapiens | adenine + 5-methylthio-D-ribose 1-phosphate | - |
? | |
additional information | enzyme plays a role in purine and polyamine metabolism and in the regulation of transmethylation reactions | Homo sapiens | ? | - |
? |