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Literature summary for 2.4.2.26 extracted from
- Menage a trois: glycogenin, proteoglycan core protein xylosyltransferase and UDP-xylose (1995), Trends Glycosci. Glycotechnol., 7, 303-332.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by CDP | Bos taurus | |
| additional information | - |
Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-alpha-D-xylose + [protein]-L-serine | Gallus gallus | - |
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? |  |
| UDP-alpha-D-xylose + [protein]-L-serine | Mus musculus | - |
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | Rattus norvegicus | - |
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | Bos taurus | - |
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | Homo sapiens | enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Gallus gallus | - |
hen | - |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cartilage | - |
Homo sapiens | - |
| cartilage | - |
Rattus norvegicus | - |
| cartilage | embryonic | Gallus gallus | - |
| chondrocyte | - |
Homo sapiens | - |
| chondrosarcoma cell | - |
Rattus norvegicus | - |
| embryo | - |
Gallus gallus | - |
| kidney | - |
Homo sapiens | - |
| kidney | - |
Rattus norvegicus | - |
| kidney | - |
Bos taurus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
| mastocytoma cell | - |
Mus musculus | - |
| oviduct | - |
Gallus gallus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | - |
Rattus norvegicus | ? | - |
? | |
| additional information | substrate preparation and specificity | Gallus gallus | ? | - |
? | |
| additional information | tripeptide SGG is a poor substrate | Homo sapiens | ? | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | - |
Gallus gallus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | - |
Mus musculus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | - |
Rattus norvegicus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | - |
Bos taurus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | exogenous protein acceptor obtained by Smith degradation of bovine chondroitin sulfate-protein complex | Gallus gallus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate | Gallus gallus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate | Mus musculus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate | Homo sapiens | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate | Rattus norvegicus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-alpha-D-xylose + [protein]-L-serine | enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein | Homo sapiens | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
| UDP-D-xylose + silk fibroin | - |
Gallus gallus | UDP + silk fibroin with xylosylserine | - |
? | |
| UDP-D-xylose + silk fibroin | - |
Homo sapiens | UDP + silk fibroin with xylosylserine | - |
? | |
| UDP-D-xylose + silk fibroin | - |
Rattus norvegicus | UDP + silk fibroin with xylosylserine | - |
? | |
| UDP-D-xylose + silk fibroin | - |
Bos taurus | UDP + silk fibroin with xylosylserine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| More | the enzyme competes for the substrate UDP-D-xylose with glycogenin, EC 2.4.1.186, which utilizes UDP-D-xylose as an alternative substrate to UDP-D-glucose | Gallus gallus |
| More | the enzyme competes for the substrate UDP-D-xylose with glycogenin, EC 2.4.1.186, which utilizes UDP-D-xylose as an alternative substrate to UDP-D-glucose | Mus musculus |
| More | the enzyme competes for the substrate UDP-D-xylose with glycogenin, EC 2.4.1.186, which utilizes UDP-D-xylose as an alternative substrate to UDP-D-glucose | Homo sapiens |
| More | the enzyme competes for the substrate UDP-D-xylose with glycogenin, EC 2.4.1.186, which utilizes UDP-D-xylose as an alternative substrate to UDP-D-glucose | Rattus norvegicus |
| More | the enzyme competes for the substrate UDP-D-xylose with glycogenin, EC 2.4.1.186, which utilizes UDP-D-xylose as an alternative substrate to UDP-D-glucose | Bos taurus |
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