Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | competitive inhibition of the acceptor substrates | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Rattus norvegicus | |
0.00011 | - |
HF-degraded chondroitin sulfate proteoglycan | - |
Rattus norvegicus | |
0.062 | - |
CDEASGIGPEVPDDRD | - |
Rattus norvegicus | |
0.062 | - |
CDEASGIGPDDRD | - |
Rattus norvegicus | |
0.11 | - |
cartilage chondroitin sulfate proteoglycan | - |
Rattus norvegicus | |
0.12 | - |
FMLEDEASGIGP | - |
Rattus norvegicus | |
0.18 | - |
UDP-D-xylose | - |
Rattus norvegicus | |
0.18 | - |
UDP-D-xylose | cosubstrate: CDEASGIGPDDRD | Rattus norvegicus | |
0.79 | - |
SDDYSGSGSG | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-xylose + [protein]-L-serine | Rattus norvegicus | - |
UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
UDP-alpha-D-xylose + [protein]-L-serine = UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | most probable mechanism: ordered single displacement with UDPxylose as the leading substrate and the xylosylated peptide as the first product released | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
chondrosarcoma cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-xylose + [protein]-L-serine | - |
Rattus norvegicus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
UDP-alpha-D-xylose + [protein]-L-serine | transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate | Rattus norvegicus | UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine | - |
? | |
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan | HF-deglycosylated acceptor | Rattus norvegicus | UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine | - |
? | |
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan | the consensus sequence, acidic-acidic-Xxx-Ser-Gly-Xxx-Gly, in the acceptor proteoglycan is important | Rattus norvegicus | UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine | - |
? | |
UDP-D-xylose + cartilage chondroitin sulfate proteoglycan | deglycosylation by Staphylococcus aureus V8 protease decreases the activity with the resulting peptides | Rattus norvegicus | UDP + cartilage chondroitin sulfate proteoglycan with xylosylserine | - |
? | |
UDP-D-xylose + CDEASGIGPDDRD | - |
Rattus norvegicus | UDP + ? | - |
? | |
UDP-D-xylose + CDEASGIGPEVPDDRD | synthetic peptide | Rattus norvegicus | UDP + CDEAS(-D-xylose)GIGPEVPDDRD | - |
? | |
UDP-D-xylose + FMLEDEASGIGP | synthetic peptide | Rattus norvegicus | UDP + FMLEDEAS(-D-xylose)GIGP | - |
? | |
UDP-D-xylose + HF-degraded chondroitin sulfate proteoglycan | - |
Rattus norvegicus | UDP + ? | - |
? | |
UDP-D-xylose + SDDYSGSGSG | synthetic peptide | Rattus norvegicus | UDP + SDDYS(-D-xylose)GSGSG | - |
? | |
UDP-D-xylose + SDDYSGSGSG | - |
Rattus norvegicus | UDP + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-D-xylose:core protein beta-D-xylosyltransferase | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | competitive inhibition of the acceptor substrates | Rattus norvegicus |