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Literature summary for 2.4.2.22 extracted from
- A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani (2006), J. Biol. Chem., 281, 16084-16089.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Leishmania donovani | either hypoxanthine-guanine phosphoribosyltransferase or xanthine phosphoribosyltransferase is absolutely essential for purine acquisition, parasite viability, and parasite infectivity of mouse macrophages | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania donovani | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | either hypoxanthine-guanine phosphoribosyltransferase or xanthine phosphoribosyltransferase is absolutely essential for purine acquisition, parasite viability, and parasite infectivity of mouse macrophages | Leishmania donovani | ? | - |
? | |
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