Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate | competitive inhibition with regard to inosine | Mycoplasma hyorhinis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.31 | - |
uridine | pH 7.6, 37°C | Mycoplasma hyorhinis | |
1.093 | - |
thymidine | pH 7.6, 37°C | Mycoplasma hyorhinis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycoplasma hyorhinis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-fluorouridine + phosphate | - |
Mycoplasma hyorhinis | 5-fluorouracil + alpha-D-ribose 1-phosphate | - |
? | |
5-iododeoxyuridine + phosphate | - |
Mycoplasma hyorhinis | 5-iodouracil + 2-deoxy-D-ribose 1-phosphate | - |
? | |
thymidine + phosphate | - |
Mycoplasma hyorhinis | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? | |
uridine + phosphate | preferred substrate | Mycoplasma hyorhinis | uracil + alpha-D-ribose 1-phosphate | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.113 | - |
substrate deoxythymidine, pH 7.6, 37°C | Mycoplasma hyorhinis | 3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate | |
0.128 | - |
substrate 5-fluorodeoxyuridine, pH 7.6, 37°C | Mycoplasma hyorhinis | 3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate | |
0.159 | - |
substrate 5-iododeoxyuridine pH 7.6, 37°C | Mycoplasma hyorhinis | 3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate | |
0.188 | - |
substrate uridine, pH 7.6, 37°C | Mycoplasma hyorhinis | 3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate |