Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Campylobacter jejuni |
Protein Variants | Comment | Organism |
---|---|---|
R216A | the mutant shows more than 50% inhibition at 0.25 mM AMP and complete loss of response to histidine while retaining its histidine-binding ability | Campylobacter jejuni |
R216Q | the mutant shows about 50% inhibition at 0.25 mM AMP, about 20% inhibition at 0.025 mM L-histidine, and about 45% inhibition at 0.25 mM ATP plus 0.025 mM L-histidine | Campylobacter jejuni |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AMP | about 10% inhibition at 0.25 mM | Campylobacter jejuni | |
L-histidine | complete inhibition at 1 mM, about 10% inhibition at 0.25 mM | Campylobacter jejuni |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | dependent on, 10 mM used in assay conditions | Campylobacter jejuni |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | Campylobacter jejuni | - |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
r | |
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | Campylobacter jejuni RM1221 | - |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | Campylobacter jejuni | - |
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | Campylobacter jejuni RM1221 | - |
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | Q5HSJ4 | - |
- |
Campylobacter jejuni RM1221 | Q5HSJ4 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Campylobacter jejuni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
Campylobacter jejuni | ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
r | |
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
Campylobacter jejuni RM1221 | ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Campylobacter jejuni | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r | |
ATP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Campylobacter jejuni RM1221 | 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
ATP-phosphoribosyltransferase | - |
Campylobacter jejuni |
ATP-PRT | - |
Campylobacter jejuni |