Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.12 extracted from

  • Feng, D.; Xu, D.; Murakoshi, N.; Tajiri, K.; Qin, R.; Yonebayashi, S.; Okabe, Y.; Li, S.; Yuan, Z.; Aonuma, K.; Ieda, M.
    Nicotinamide phosphoribosyltransferase (Nampt)/nicotinamide adenine dinucleotide (NAD) axis suppresses atrial fibrillation by modulating the calcium handling pathway (2020), Int. J. Mol. Sci., 21, 4655 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.2.12

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nicotinamide D-ribonucleotide + diphosphate Mus musculus
-
 nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q99KQ4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinamide D-ribonucleotide + diphosphate
-
 Mus musculus nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
Nampt
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus high fat diet reduces enzyme expression in the atrial tissues down

General Information

General Information Comment Organism
malfunction partial deletion of the enzyme facilitates high-fat diet-induced atrial fibrillation through increased diastolic calcium leaks Mus musculus