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Literature summary for 2.4.2.12 extracted from

  • Marletta, A.S.; Massarotti, A.; Orsomando, G.; Magni, G.; Rizzi, M.; Garavaglia, S.
    Crystal structure of human nicotinic acid phosphoribosyltransferase (2015), FEBS Open Bio, 5, 419-428.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
FK866 potent competitive inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate Homo sapiens
-
nicotinamide D-ribonucleotide + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P43490
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens nicotinamide D-ribonucleotide + diphosphate
-
?

Synonyms

Synonyms Comment Organism
NMPRTase
-
Homo sapiens