General Stability | Organism |
---|---|
freeze-thawing inactivates | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | nicotinic acid, thymine, 5-bromouracil | Homo sapiens | |
NAD+ | - |
Homo sapiens | |
nicotinate adenine dinucleotide | not inhibitory | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0016 | - |
nicotinamide | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | Homo sapiens | - |
nicotinamide D-ribonucleotide + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | diploid, GM 1362, from patient with Lesch-Nyhan disease | Homo sapiens | - |
Storage Stability | Organism |
---|---|
-80°C, crude, 4-6 months | Homo sapiens |
4°C, crude, inactivation overnight | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Homo sapiens | nicotinamide D-ribonucleotide + diphosphate | - |
? | |
nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate | specific for nicotinamide, no substrates: thymine, 5-bromouracil, nicotinic acid adenine dinucleotide | Homo sapiens | nicotinamide D-ribonucleotide + diphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | requirement | Homo sapiens |