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Literature summary for 2.4.2.1 extracted from

  • Zhu, S.; Ren, L.; Wang, J.; Zheng, G.; Tang, P.
    Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix (2012), Bioorg. Med. Chem. Lett., 22, 2102-2104.
    View publication on PubMed

Application

Application Comment Organism
synthesis two-step efficient synthesis of 5-methyluridine, a intermediate in the synthesis of anti-AIDS drug such as stavudine and zidovudine Aeropyrum pernix

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Aeropyrum pernix

Organism

Organism UniProt Comment Textmining
Aeropyrum pernix
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Aeropyrum pernix

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanosine + phosphate
-
Aeropyrum pernix guanine + alpha-D-ribose 1-phosphate
-
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