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Literature summary for 2.4.2.1 extracted from

  • Kang, Y.N.; Zhang, Y.; Allan, P.W.; Parker, W.B.; Ting, J.W.; Chang, C.Y.; Ealick, S.E.
    Structure of grouper iridovirus purine nucleoside phosphorylase (2010), Acta Crystallogr. Sect. D, 66, 155-162.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
to 2.4 A resolution, space group R3. alpha/beta structure with a nine-stranded mixed beta-barrel flanked by a total of nine alpha-helices. The predicted phosphate-binding and ribose-binding sites are occupied by a phosphate ion and a Tris molecule, respectively grouper iridovirus

Organism

Organism UniProt Comment Textmining
grouper iridovirus
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00075
-
substrate adenosine, pH 7.4 grouper iridovirus
0.95
-
substrate 2'-deoxyinosine, pH 7.4 grouper iridovirus
1.17
-
substrate 2'-deoxyguanosine, pH 7.4 grouper iridovirus
2.2
-
substrate guanosine, pH 7.4 grouper iridovirus
3.47
-
substrate inosine, pH 7.4 grouper iridovirus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyguanosine + phosphate
-
grouper iridovirus guanine + alpha-D-2-deoxyribose 1-phosphate
-
?
2'-deoxyinosine + phosphate
-
grouper iridovirus alpha-D-2-deoxyribose 1-phosphate + hypoxanthine
-
?
adenosine + phosphate
-
grouper iridovirus adenine + alpha-D-ribose 1-phosphate
-
?
guanosine + phosphate
-
grouper iridovirus guanine + alpha-D-ribose 1-phosphate
-
?
inosine + phosphate
-
grouper iridovirus hypoxanthine + alpha-D-ribose 1-phosphate
-
?