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Literature summary for 2.4.2.1 extracted from
- Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver (1976), Biochim. Biophys. Acta, 422, 15-28.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-chloroadenosine | inhibits ribosylation of adenine and N6-furfuryladenine | Rattus norvegicus |  |
| Inosine | inhibits ribosylation of hypoxanthine and guanine | Rattus norvegicus | |
| PCMB | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
adenine phosphorylase activity and a distinct inosine-guanosine phosphorylase activity | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| adenosine + phosphate | - |
Rattus norvegicus | adenine + alpha-D-ribose 1-phosphate | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| additional information | - |
adenine selectively protects the adenosine phosphorylase against heat inactivation, no effect on inosine-guanosine phosphorylase. Hypoxanthine selectively protects inosine-guanosine phosphorylase activity, no effect on adenosine phosphorylase | Rattus norvegicus |
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