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Literature summary for 2.4.1.90 extracted from

  • Zhang, S.; Cai, M.; Zhang, S.W.; Hu, Y.; Gu, J.X.
    Involvement of beta 1,4 galactosyltransferase I and Gal beta1-4GlcNAc groups in human hepatocarcinoma cell apoptosis (2003), Mol. Cell. Biochem., 243, 81-86.
    View publication on PubMed
Search for more literature for 2.4.1.90

Cloned(Commentary)

Cloned (Comment) Organism
transient functional overexpression in 7721 hepatocarcinoma cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information the enzyme transfected 7721 hepatocarcinoma cell line is more susceptible to cycloheximide-induced apoptosis than the wild-type cells, cells show increased enzyme activity and expression of Galbeta1,4GlcNAc groups on the cell surface Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose + N-acetyl-D-glucosamine Homo sapiens synthesis of Galbeta1,4GlcNAc groups in N-linked sugar chains of glycoproteins involved in many physiological functions, e.g. sperm-egg interactions, cell migration, and embryonic development, enzyme expression is highly increased during cycloheximide-induced cell apoptosis in liver carcinoma UDP + N-acetyllactosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose + N-acetyl-D-glucosamine
-
 Homo sapiens UDP + N-acetyllactosamine
-
 ?
UDP-galactose + N-acetyl-D-glucosamine synthesis of Galbeta1,4GlcNAc groups in N-linked sugar chains of glycoproteins involved in many physiological functions, e.g. sperm-egg interactions, cell migration, and embryonic development, enzyme expression is highly increased during cycloheximide-induced cell apoptosis in liver carcinoma Homo sapiens UDP + N-acetyllactosamine
-
 ?

Synonyms

Synonyms Comment Organism
beta 1,4 galactosyltransferase I
-
 Homo sapiens
beta 1,4GTI
-
 Homo sapiens