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Literature summary for 2.4.1.90 extracted from

  • Nakazawa, K.; Furukawa, K.; Narimatsu, H.; Kobata, A.
    Kinetic study of human beta-1,4-galactosyltransferase expressed in E. coli (1993), J. Biochem., 113, 747-753.
    View publication on PubMed
Search for more literature for 2.4.1.90

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.025
-
 UDPgalactose recombinant enzyme Homo sapiens
0.064
-
 asialo-agalacto-transferrin recombinant enzyme Homo sapiens
0.17
-
 agalacto-poly-N-acetyllactosamine
-
 Homo sapiens
0.19
-
 lacto-N-triose II
-
 Homo sapiens
0.83
-
 lacto-N-triaosylceramide
-
 Homo sapiens
2.5
-
 N-acetylglucosamine recombinant enzyme Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 x * 38000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides Homo sapiens the enzyme may be involved in the synthesis of poly-N-acetyllactosamine, lacto-N-neotetraose and probably lacto-N-neotetraosylceramide in addition to the formation of the Galbeta1-4GlcNAc group of glycoprotein sugar chains and lactose ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-galactose + asialo-agalacto-transferrin
-
 Homo sapiens ?
-
 ?
UDPgalactose + agalacto-poly-N-acetyllactosamine
-
 Homo sapiens ?
-
 ?
UDPgalactose + lacto-N-triaosylceramide
-
 Homo sapiens ?
-
 ?
UDPgalactose + lacto-N-triose II
-
 Homo sapiens ?
-
 ?
UDPgalactose + N-acetylglucosaminyl at the non-reducing ends of protein-bound oligosaccharides the enzyme may be involved in the synthesis of poly-N-acetyllactosamine, lacto-N-neotetraose and probably lacto-N-neotetraosylceramide in addition to the formation of the Galbeta1-4GlcNAc group of glycoprotein sugar chains and lactose Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 38000, SDS-PAGE Homo sapiens