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Literature summary for 2.4.1.83 extracted from

  • Jadid, N.; Mialoundama, A.S.; Heintz, D.; Ayoub, D.; Erhardt, M.; Mutterer, J.; Meyer, D.; Alioua, A.; Van Dorsselaer, A.; Rahier, A.; Camara, B.; Bouvier, F.
    Dolichol phosphate mannose synthase1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis (2011), Plant Cell, 23, 1985-2005.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
Arabidopsis thaliana 5783
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membrane
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Arabidopsis thaliana 16020
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Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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ecotype Columbia
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Purification (Commentary)

Purification (Comment) Organism
DEAE-cellulose column chromatography, gel filtration Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
leaf
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Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-mannose + dolichyl phosphate
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Arabidopsis thaliana GDP + dolichyl D-mannosyl phosphate
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?
additional information two binding proteins, DPMS2 and DPMS3 serve as membrane anchors for DPMS1 or provide catalytic assistance. Recombinant DPMS1 alone does not catalyze dolichyl D-mannosyl phosphate synthesis Arabidopsis thaliana ?
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?

Synonyms

Synonyms Comment Organism
Dol-P-Man synthase1
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Arabidopsis thaliana
DPMS1
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Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction loss-of-function mutations and RNA interference-mediated reduction of DPMS1 expression in Arabidopsis causes a wrinkled seed coat phenotype and most remarkably enhanced hypersensitivity to ammonium that is manifested by extensive chlorosis and a strong reduction of root growth Arabidopsis thaliana
physiological function overexpression of DPMS1 in Arabidopsis thaliana results in disorganized stem morphology and vascular bundle arrangements, wrinkled seed coat, and constitutive ER stress response Arabidopsis thaliana