Application | Comment | Organism |
---|---|---|
medicine | D-P-M enzyme activity represents a potentially useful approach to address the problem of porcine endogenous retrovirus infections in clinical xenotransplantations | Sus scrofa |
Cloned (Comment) | Organism |
---|---|
cDNA fragments containing the start and stop codons amplified and subcloned into the EcoRV site of the pBluescript II SK(-) cloning vector | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Synonyms | Comment | Organism |
---|---|---|
D-P-M | - |
Sus scrofa |
dolichyl-phosphate mannosyltransferase | - |
Sus scrofa |
Organism | Comment | Expression |
---|---|---|
Sus scrofa | compared with the mock line, the temporary PEC(Z)/PB lines show a decreased mRNA expression for D-P-M and a clear destruction of porcine endogenous retrovirus infectivity to human cells in the Lac Z pseudotype assay. Compared with parental and mock cells, all PEC(Z)/PB cells transfected with siRNA show a decreased mRNA expression for the D-P-M by one-fifth | down |