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Literature summary for 2.4.1.83 extracted from

  • Villagomez-Castro, J.C.; Calvo-Mendez, C.; Flores-Carreon, A.; Lopez-Romero, E.
    Partial purification and characterization of dolichol phosphate mannose synthase from Entamoeba histolytica (2000), Glycobiology, 10, 1311-1316.
    View publication on PubMed
Search for more literature for 2.4.1.83

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylcholine increases activity 1.3fold at the optimal concentration Entamoeba histolytica
phosphatidylethanolamine increases activity 2.3fold at the optimal concentration Entamoeba histolytica
phosphatidylinositol increases activity 2.3fold at the optimal concentration Entamoeba histolytica

General Stability

General Stability Organism
reducing agents positively influence stability Entamoeba histolytica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.005
-
 GDPmannose unphosphorylated enzyme Entamoeba histolytica
0.0065
-
 GDPmannose phosphorylated enzyme Entamoeba histolytica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDPmannose + dolichyl phosphate Entamoeba histolytica essential enzyme in glycoprotein biosynthesis GDP + dolichyl D-mannosyl phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Entamoeba histolytica

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Entamoeba histolytica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDPmannose + dolichyl phosphate
-
 Entamoeba histolytica GDP + dolichyl D-mannosyl phosphate
-
 ?
GDPmannose + dolichyl phosphate essential enzyme in glycoprotein biosynthesis Entamoeba histolytica GDP + dolichyl D-mannosyl phosphate
-
 ?