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Literature summary for 2.4.1.80 extracted from

  • Patwardhan, G.; Zhang, Q.; Yin, D.; Gupta, V.; Bao, J.; Senkal, C.; Ogretmen, B.; Cabot, M.; Shah, G.; Sylvester, P.; Jazwinski, S.; Liu, Y.
    A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis (2009), PLoS ONE, 4, e6938.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Synonyms

Synonyms Comment Organism
GCS
-
Mus musculus
GCS
-
Homo sapiens
glucosylceramide synthase
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Mus musculus
glucosylceramide synthase
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Homo sapiens

Expression

Organism Comment Expression
Mus musculus the mixed-backbone oligonucleotide MBO-asGCS considerable decreases mRNA levels in murine tumor cell lines down
Homo sapiens the mixed-backbone oligonucleotide MBO-asGCS decreases mRNA levels in human tumor cell lines by 65% down