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Literature summary for 2.4.1.80 extracted from

  • Marza, E.; Simonsen, K.T.; Faergeman, N.J.; Lesa, G.M.
    Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells (2009), J. Cell Sci., 122, 822-833.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
additional information animals lacking CGT do not synthesize glycosphingolipids, arrest growth at the first larval stage, and display defects in a subset of cells in their digestive tract, restoring CGT function in these digestive tract cells but not in a variety of other tissues is sufficient to rescue the phenotypes associated with loss of CGT function Caenorhabditis elegans

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane
-
 Caenorhabditis elegans 139
-

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 mutants without CGT
-
Caenorhabditis elegans
-
 isoform B; mutants without CGT
-
Caenorhabditis elegans
-
 isoform d; mutants without CGT
-
Caenorhabditis elegans O18037 mutants without CGT
-
Caenorhabditis elegans Q21054 isoform A; mutants without CGT
-
Caenorhabditis elegans Q21054 isoform c; mutants without CGT
-

Source Tissue

Source Tissue Comment Organism Textmining
digestive tract
-
 Caenorhabditis elegans
-

Synonyms

Synonyms Comment Organism
ceramide glucosyltransferase
-
 Caenorhabditis elegans
CGT
-
 Caenorhabditis elegans
cgt-1 the Caenorhabditis elegans genome encodes three ceramide glucosyltransferase (CGT) genes Caenorhabditis elegans
cgt-2 the Caenorhabditis elegans genome encodes three ceramide glucosyltransferase (CGT) genes Caenorhabditis elegans
cgt-3 the Caenorhabditis elegans genome encodes three ceramide glucosyltransferase (CGT) genes Caenorhabditis elegans