Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.78 extracted from

  • Jankowski, W.; Mankowski, T.; Chojnacki, T.
    Formation of polyprenol monophosphate glucose in Shigella flexneri (1974), Biochim. Biophys. Acta, 337, 153-162.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
deoxycholate stimulates solubilized activity Shigella flexneri
taurocholate stimulates solubilized activity Shigella flexneri
Triton X-100 stimulates solubilized activity Shigella flexneri

General Stability

General Stability Organism
Triton X-100, taurocholate or deoxycholate stabilizes Shigella flexneri

Inhibitors

Inhibitors Comment Organism Structure
UDP not UMP Shigella flexneri

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Shigella flexneri 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-glucose + ficaprenol phosphate Shigella flexneri
-
UDP + ficaprenolphosphate-glucose
-
?

Organism

Organism UniProt Comment Textmining
Shigella flexneri
-
strain 2a, not strain Y
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-glucose + ficaprenol phosphate
-
Shigella flexneri UDP + ficaprenolphosphate-glucose
-
?
UDP-glucose + ficaprenol phosphate i.e. mixture of C50, C55 and C66 cis- and trans-polyprenols, most effective lipid glucosylacceptor, phosphate esters of phytol, betulaprenol, mixture of C30-C45 cis- and trans-polyprenols and solanesol, C45 all-trans polyprenol and dolichol, mainly C95 cis- and trans-polyprenols, containing saturated alpha-isoprene residue are poor substrates, UDP-galactose replaces UDP-glucose with crude membrane-preparations, but the product is ficaprenolphosphate-glucose. No substrates are GDP-mannose, UDP-glucuronic acid and UDP-N-acetylglucosamine Shigella flexneri UDP + ficaprenolphosphate-glucose
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Shigella flexneri

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Shigella flexneri