Literature summary for 2.4.1.69 extracted from

Silva, L.M.; Carvalho, A.S.; Guillon, P.; Seixas, S.; Azevedo, M.; Almeida, R.; Ruvoen-Clouet, N.; Reis, C.A.; Le Pendu, J.; Rocha, J.; David, L.
Infection-associated FUT2 (Fucosyltransferase 2) genetic variation and impact on functionality assessed by in vivo studies (2010), Glycoconj. J., 27, 61-68.

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Cloned(Commentary)

Cloned (Comment)	Organism
subcloned in CHO-K1 cells	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
L101F	spontaneous missense mutation frequent in Asian populations	Homo sapiens
additional information	bp428 G>A is a spontaneous nonsense mutation, 739G > A substitution does not inactivate the enzyme	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
alpha-1,2-fucosyltransferase	-	Homo sapiens
fucosyltransferase 2	-	Homo sapiens
FUT2	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	Biosynthesis of cell surface glycoconjugates, which play a role in infections. For example, nonsecretors are known to be virtually resistant to infection by norovirus. Inversely, women with the nonsecretor phenotype are more prone to Escherichia coli mediated recurrent urinary tract infections than secretor women.	Homo sapiens

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Release 2023.1 (January 2023)